Ribosome Inactivating Proteins
- Name
- Ribosome Inactivating Proteins
- Accession Number
- DBCAT003076
- Description
N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
- Drugs
Drug Drug Description Aviscumine Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy). XMMME-001-RTA Not Annotated XomaZyme-791 Not Annotated - Drugs & Drug Targets
Drug Target Type