Echinocandins
- Name
- Echinocandins
- Accession Number
- DBCAT003671
- Description
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
- Drugs
Drug Drug Description Anidulafungin An antifungal used in the treatment of several types of candida infections. Caspofungin An echinocandin used to treat a variety of fungal infections. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Rezafungin An echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis. - Drugs & Drug Targets