Diterpene Alkaloids
- Name
- Diterpene Alkaloids
- Accession Number
- DBCAT005816
- Description
Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS.
- Drugs
Drug Drug Description Gibberellic acid Not Available Gibberellin A4 Not Available Salvinorin A Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. Steviolbioside Steviolbioside has been used in trials studying the treatment of HIV-1 Infection. Rebaudioside A Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus). Isosteviol Not Annotated Stevioside Not Annotated - Drugs & Drug Targets
Drug Target Type Gibberellic acid Arylacetamide deacetylase-like 2 target Gibberellin A4 Arylacetamide deacetylase-like 2 target