Antineoplastic cell and gene therapy

Name
Antineoplastic cell and gene therapy
Accession Number
DBCAT005827
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
Sitimagene ceradenovecIntended for the treatment of brain cancer.
TisagenlecleucelA CAR T cell therapy for relapsed or refractory large B-cell lymphoma and diffuse large B-cell lymphoma.
Talimogene laherparepvecA genetically modified virus used to treat recurrent melanoma, or metastatic melanoma.
Axicabtagene ciloleucelA CAR T-cell therapy used to treat adults with large B-cell lymphomas and follicular lymphoma.
Brexucabtagene autoleucelA modified autologous chimeric antigen receptor (CAR) T cell therapy employing a modified murine anti-CD19 single-chain variable fragment linked to CD28 and CD3ΞΆ co-stimulatory domains for the treatment of patients with relapsed and refractory mantle cell lymphoma.
Idecabtagene vicleucelAn autologous T-cell therapy indicated to treat relapsed or refractory multiple myeloma.
Ciltacabtagene autoleucelA BCMA-directed CAR T-cell therapy used in the treatment of relapsed or refractory multiple myeloma in previously treated patients.
Drugs & Drug Targets
DrugTargetType
TisagenlecleucelB-lymphocyte antigen CD19target
Talimogene laherparepvecHeparan sulfatetarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
Axicabtagene ciloleucelB-lymphocyte antigen CD19target
Brexucabtagene autoleucelB-lymphocyte antigen CD19target
Idecabtagene vicleucelTumor necrosis factor receptor superfamily member 17target
Ciltacabtagene autoleucelTumor necrosis factor receptor superfamily member 17target