(-)-menthol 1-propylene glycol carbonate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
(-)-menthol 1-propylene glycol carbonate
Accession Number
DB14136
Type
Small Molecule
Groups
Experimental
Description
Not Available
Structure
Thumb
Synonyms
  • (-)-menthol (+/-)-1-propylene glycol carbonate
  • 2-hydroxypropyl ((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) carbonate
  • Carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
  • Fema no. 3806, 1-propylene glycol carbonate
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Thera Derm Roll On(-)-menthol 1-propylene glycol carbonate (9 mg/90mg) + Camphor (4 mg/90mg) + Methyl salicylate 2-ethylbutyrate (18 mg/90mg) + Peppermint oil (9 mg/90mg)LiquidTopicalManna Omni International Incorporated2017-07-31Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Thera Derm Roll On(-)-menthol 1-propylene glycol carbonate (9 mg/90mg) + Camphor (4 mg/90mg) + Methyl salicylate 2-ethylbutyrate (18 mg/90mg) + Peppermint oil (9 mg/90mg)LiquidTopicalManna Omni International Incorporated2017-07-31Not applicableUs
Categories
Not Available
UNII
2WL8FX4EEZ
CAS number
260781-16-6
Weight
Average: 258.358
Monoisotopic: 258.183109317
Chemical Formula
C14H26O4
InChI Key
FLYJSXDJKBHQAU-IBSWDFHHSA-N
InChI
InChI=1S/C14H26O4/c1-9(2)12-6-5-10(3)7-13(12)18-14(16)17-8-11(4)15/h9-13,15H,5-8H2,1-4H3/t10-,11?,12+,13-/m1/s1
IUPAC Name
1-[({[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}carbonyl)oxy]propan-2-ol
SMILES
[H]C(C)(O)COC(=O)O[C@]1([H])C[C@]([H])(C)CC[C@@]1([H])C(C)C

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
23350593
RxNav
1371320

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.194 mg/mLALOGPS
logP3.18ALOGPS
logP3.45ChemAxon
logS-3.1ALOGPS
pKa (Strongest Acidic)14.82ChemAxon
pKa (Strongest Basic)-2.9ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area55.76 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity68.93 m3·mol-1ChemAxon
Polarizability29.72 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Classification
Not classified

Drug created on June 27, 2018 11:23 / Updated on March 01, 2020 21:46

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