NAV

Myrtecaine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Myrtecaine is a local anesthetic used in topical products.

Generic Name
Myrtecaine
DrugBank Accession Number
DB15785
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 265.441
Monoisotopic: 265.240564622
Chemical Formula
C17H31NO
Synonyms
  • Mirtecaina
  • Myrtecaine
  • Myrtecainum
  • Nopoxamine
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Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatAcute muscle painCombination Product in combination with: Salicylic acid (DB00936)••••••••••••••••••••
Used in combination to treatArm painCombination Product in combination with: Salicylic acid (DB00936)••• ••••••••
Used in combination to treatBack pain lower backCombination Product in combination with: Salicylic acid (DB00936)••• ••••••••
Used in combination to treatBruisesCombination Product in combination with: Salicylic acid (DB00936)••• ••••••••
Used in combination to treatJoint painCombination Product in combination with: Salicylic acid (DB00936)••• ••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Myrtecaine citrateNot Available68342-79-0VEKFCVMAXIUDFU-UHFFFAOYSA-N
Myrtecaine hydrochlorideNot Available68342-78-9XHEAFBNXHWYLFE-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Algesal 10 %/1 % - CremeMyrtecaine (1 %) + Diethylamine salicylate (10 %)CreamTopicalPharmaselect International Beteiligungs Gmb H1995-08-25Not applicableAustria flag
ALGESAL SURACTİVE %10 + %1 MERHEM, 40 GRMyrtecaine (0.01 g/g) + Salicylic acid (0.1 g/g)OintmentTopicalRECORDATİ İLAÇ SAN. VE TİC. A.Ş.1970-07-27Not applicableTurkey flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
9902116282
CAS number
7712-50-7
InChI Key
BZRYYBWNOUALTQ-HOTGVXAUSA-N
InChI
InChI=1S/C17H31NO/c1-5-18(6-2)10-12-19-11-9-14-7-8-15-13-16(14)17(15,3)4/h7,15-16H,5-6,8-13H2,1-4H3/t15-,16-/m0/s1
IUPAC Name
(2-{2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethoxy}ethyl)diethylamine
SMILES
CCN(CC)CCOCCC1=CC[C@H]2C[C@@H]1C2(C)C

References

General References
  1. BASG: Algesal (Myrtecaine and Salicylic Acid) Topical Cream [Link]
ChemSpider
32697374
RxNav
59082
ChEBI
135096
Wikipedia
Myrtecaine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CreamTopical
OintmentTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0288 mg/mLALOGPS
logP4.6ALOGPS
logP3.18Chemaxon
logS-4ALOGPS
pKa (Strongest Basic)9.41Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area12.47 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity83.52 m3·mol-1Chemaxon
Polarizability33.88 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-0190000000-188cefbf6266adf2ae75
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-0190000000-ae2cedc7e8dc687e2458
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0uxr-1930000000-22e84bfe0e8900dd898c
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-02t9-1950000000-afd846475773fe3c4584
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-4900000000-3e0c052be1709adc4285
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-00ko-4910000000-22196916551d0b087fa0
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at August 24, 2020 13:56 / Updated at May 14, 2021 01:08