AZD-1940
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- AZD-1940
- DrugBank Accession Number
- DB17077
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 413.53
Monoisotopic: 413.194854686 - Chemical Formula
- C20H29F2N3O2S
- Synonyms
- Ethanesulfonamide, n-(1-((4,4-difluorocyclohexyl)methyl)-2-(1,1-dimethylethyl)-1h-benzimidazol-5-yl)-
- External IDs
- ART-2713
- AZD 1940
- AZD-1940
- NEO-1940
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0J0035E9FT
- CAS number
- 881413-29-2
- InChI Key
- ZAGGGZCIFUQHOH-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H29F2N3O2S/c1-5-28(26,27)24-15-6-7-17-16(12-15)23-18(19(2,3)4)25(17)13-14-8-10-20(21,22)11-9-14/h6-7,12,14,24H,5,8-11,13H2,1-4H3
- IUPAC Name
- N-{2-tert-butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-1,3-benzodiazol-5-yl}ethane-1-sulfonamide
- SMILES
- CCS(=O)(=O)NC1=CC=C2N(CC3CCC(F)(F)CC3)C(=NC2=C1)C(C)(C)C
References
- General References
- Not Available
- External Links
- ChemSpider
- 9850723
- BindingDB
- 50536919
- ChEMBL
- CHEMBL4550236
- Wikipedia
- AZD-1940
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Pain 1 1 Completed Treatment Back Pain Lower Back 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0406 mg/mL ALOGPS logP 4.36 ALOGPS logP 3.89 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 9.11 Chemaxon pKa (Strongest Basic) 6.18 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 63.99 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 105.9 m3·mol-1 Chemaxon Polarizability 43.94 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at October 24, 2022 18:28 / Updated at December 01, 2022 11:34