KL1333
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- KL1333
- DrugBank Accession Number
- DB17622
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 240.262
Monoisotopic: 240.089877634 - Chemical Formula
- C14H12N2O2
- Synonyms
- 2-(1-methylethyl)-3h-naphth(1,2-d)imidazole-4,5-dione
- 2-isopropyl-3h-naphtho(1,2-d)imidazole-4,5-dione
- 2-isopropyl-3H-naphtho[1,2-d]imidazole-4,5-dione
- 3h-naphth(1,2-d)imidazole-4,5-dione, 2-(1-methylethyl)-
- External IDs
- KL 1333
- KL-1333
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- NA2ZOL5UGM
- CAS number
- 1800405-30-4
- InChI Key
- AJFWITSBVLLDCC-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H12N2O2/c1-7(2)14-15-10-8-5-3-4-6-9(8)12(17)13(18)11(10)16-14/h3-7H,1-2H3,(H,15,16)
- IUPAC Name
- 2-(propan-2-yl)-3H,4H,5H-naphtho[1,2-d]imidazole-4,5-dione
- SMILES
- CC(C)C1=NC2=C(N1)C(=O)C(=O)C1=CC=CC=C21
References
- General References
- Not Available
- External Links
- ChemSpider
- 68007161
- ChEMBL
- CHEMBL4594430
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Active Not Recruiting Treatment Primary Mitochondrial Diseases 1 1 Completed Treatment Mitochondrial Disorders 1 1 Completed Treatment Mitochondrial Disorders / Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) / Mitochondrial Myopathies / Mitochondrial Respiratory Chain Deficiencies 1 1 Completed Treatment Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) / Mitochondrial Respiratory Chain Deficiencies 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 2.47 Chemaxon pKa (Strongest Acidic) 9.43 Chemaxon pKa (Strongest Basic) 4.26 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 62.82 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 67.25 m3·mol-1 Chemaxon Polarizability 25.58 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at April 13, 2023 17:26 / Updated at July 18, 2023 22:59