Enlarged Prostate

Also known as: Prostatomegaly / Benign prostatic hyperplasia without lower urinary tract symptoms / Benign prostatic hyperplasia / Large prostate (finding)

Drug	Drug Name	Drug Description
DB01126	Dutasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
DB01216	Finasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.

Drug	Drug Name	Target	Type
DB01126	Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	target
DB01126	Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	target
DB01126	Dutasteride	Sodium-dependent dopamine transporter	transporter
DB01126	Dutasteride	Synaptic vesicular amine transporter	transporter
DB01126	Dutasteride	Serum albumin	carrier
DB01126	Dutasteride	Alpha-1-acid glycoprotein 1	carrier
DB01126	Dutasteride	Cytochrome P450 3A5	enzyme
DB01216	Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	target
DB01216	Finasteride	Cytochrome P450 3A4	enzyme
DB01216	Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	target
DB01216	Finasteride	3-oxo-5-beta-steroid 4-dehydrogenase	target
DB01216	Finasteride	Cytochrome P450 3A5	enzyme
DB01216	Finasteride	Cytochrome P450 3A7	enzyme
DB01216	Finasteride	Solute carrier family 12 member 5	transporter

Drug	Drug Name	Phase	Status	Count
DB01216	Finasteride	2	Completed	1
DB05493	NX-1207	2	Completed	1
DB01216	Finasteride	3	Completed	2
DB06266	Lonidamine	3	Terminated	1
DB00820	Tadalafil	3	Completed	1