Refractory Cutaneous T-cell Lymphoma

Also known as: Cutaneous T-cell lymphoma refractory / Refractory Cutaneous T-Cell Lymphoma (CTCL)

Drug	Drug Name	Drug Description
DB00307	Bexarotene	A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
DB00553	Methoxsalen	A furocoumarin used to treat psoriasis and vitiligo.

Drug	Drug Name	Target	Type
DB00307	Bexarotene	Retinoic acid receptor RXR-beta	target
DB00307	Bexarotene	Cytochrome P450 3A4	enzyme
DB00307	Bexarotene	Retinoic acid receptor RXR-alpha	target
DB00307	Bexarotene	Retinoic acid receptor RXR-gamma	target
DB00307	Bexarotene	Cytochrome P450 2C8	enzyme
DB00553	Methoxsalen	DNA	target
DB00553	Methoxsalen	Cytochrome P450 2A6	enzyme
DB00553	Methoxsalen	Cytochrome P450 1A2	enzyme
DB00553	Methoxsalen	Cytochrome P450 1A1	enzyme
DB00553	Methoxsalen	Cytochrome P450 2A13	enzyme

Drug	Drug Name	Phase	Status	Count
DB12498	Mogamulizumab	2	Active Not Recruiting	1
DB00307	Bexarotene	4	Completed	1