Acute Agitation

Also known as: Agitation / Excitement abnormal / Feeling agitated / Agitated

DrugDrug NameDrug Description
DB00408LoxapineA antipsychotic used for the treatment of schizophrenia.
DB00334OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
DB00246ZiprasidoneAn atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.
DrugDrug NameTargetType
DB00408LoxapineDopamine D1 receptortarget
DB00408LoxapineDopamine D2 receptortarget
DB00408Loxapine5-hydroxytryptamine receptor 2Atarget
DB00408Loxapine5-hydroxytryptamine receptor 2Ctarget
DB00408Loxapine5-hydroxytryptamine receptor 1Atarget
DB00408Loxapine5-hydroxytryptamine receptor 1Btarget
DB00408Loxapine5-hydroxytryptamine receptor 1Dtarget
DB00408Loxapine5-hydroxytryptamine receptor 1Etarget
DB00408Loxapine5-hydroxytryptamine receptor 3Atarget
DB00408Loxapine5-hydroxytryptamine receptor 5Atarget
DB00408Loxapine5-hydroxytryptamine receptor 6target
DB00408Loxapine5-hydroxytryptamine receptor 7target
DB00408LoxapineAlpha-1A adrenergic receptortarget
DB00408LoxapineAlpha-1B adrenergic receptortarget
DB00408LoxapineAlpha-2A adrenergic receptortarget
DB00408LoxapineAlpha-2B adrenergic receptortarget
DB00408LoxapineAlpha-2C adrenergic receptortarget
DB00408LoxapineBeta-1 adrenergic receptortarget
DB00408LoxapineMuscarinic acetylcholine receptor M1target
DB00408LoxapineMuscarinic acetylcholine receptor M2target
DB00408LoxapineMuscarinic acetylcholine receptor M3target
DB00408LoxapineMuscarinic acetylcholine receptor M4target
DB00408LoxapineMuscarinic acetylcholine receptor M5target
DB00408LoxapineD(1) dopamine receptortarget
DB00408LoxapineDopamine D3 receptortarget
DB00408LoxapineDopamine D4 receptortarget
DB00408LoxapineDopamine D5 receptortarget
DB00408LoxapineHistamine H1 receptortarget
DB00408LoxapineHistamine H2 receptortarget
DB00408LoxapineHistamine H4 receptortarget
DB00408LoxapineSodium-dependent serotonin transportertarget
DB00408LoxapineSodium-dependent noradrenaline transportertarget
DB00408LoxapineSodium-dependent dopamine transportertarget
DB00334OlanzapineDopamine D1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineDopamine D4 receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineDopamine D2 receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineDopamine D3 receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineDopamine D5 receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineP-glycoprotein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineBeta adrenergic receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 1target
DB00334OlanzapineGABA-A receptor (benzodiazepine site)target
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineUDP-glucuronosyltransferase 1-4enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334OlanzapineCytochrome P450 3A Subfamilyenzyme
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneDopamine D2 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneDopamine D3 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneDopamine D4 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneDopamine D1 receptortarget
DB00246ZiprasidoneDopamine D5 receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00246ZiprasidoneAldehyde oxidaseenzyme
DrugDrug NamePhaseStatusCount
DB00334Olanzapine1Completed1
DB00829Diazepam4Recruiting1
DB00502Haloperidol4Recruiting1
DB00334Olanzapine4Recruiting1