Multidrug resistant HIV-1 infection

Also known as: Multi-Drug Resistant Hiv-1 Infection

Drug	Drug Name	Drug Description
DB11796	Fostemsavir	An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
DB12698	Ibalizumab	A CD4-specific antibody used to treat HIV infections.
DB15673	Lenacapavir	A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment.

Drug	Drug Name	Target	Type
DB11796	Fostemsavir	Cytochrome P450 3A4	enzyme
DB11796	Fostemsavir	UDP-glucuronosyltransferases (UGTs)	enzyme
DB11796	Fostemsavir	P-glycoprotein 1	transporter
DB11796	Fostemsavir	ATP-binding cassette sub-family G member 2	transporter
DB11796	Fostemsavir	Solute carrier organic anion transporter family member 1B1	transporter
DB11796	Fostemsavir	Solute carrier organic anion transporter family member 1B3	transporter
DB11796	Fostemsavir	Serum albumin	carrier
DB11796	Fostemsavir	Envelope glycoprotein gp160	target
DB12698	Ibalizumab	T-cell surface glycoprotein CD4	target
DB12698	Ibalizumab	C-C chemokine receptor type 5	target
DB12698	Ibalizumab	C-X-C chemokine receptor type 4	target
DB15673	Lenacapavir	Gag-Pol polyprotein	target
DB15673	Lenacapavir	Cytochrome P450 3A4	enzyme
DB15673	Lenacapavir	UDP-glucuronosyltransferase 1-1	enzyme
DB15673	Lenacapavir	P-glycoprotein 1	transporter

Drug	Drug Name	Phase	Status	Count