Endocrine Therapy

Also known as: Hormone therapy / Hormone therapy (procedure)

Drug	Drug Name	Drug Description
DB12001	Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.
DB09074	Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.

Drug	Drug Name	Target	Type
DB12001	Abemaciclib	Multidrug and toxin extrusion protein 1	transporter
DB12001	Abemaciclib	Multidrug and toxin extrusion protein 2	transporter
DB12001	Abemaciclib	Cyclin-dependent kinase 4	target
DB12001	Abemaciclib	Cyclin-dependent kinase 6	target
DB12001	Abemaciclib	Serum albumin	carrier
DB12001	Abemaciclib	alpha1-acid glycoprotein	carrier
DB12001	Abemaciclib	Cytochrome P450 3A4	enzyme
DB12001	Abemaciclib	P-glycoprotein 1	transporter
DB12001	Abemaciclib	ATP-binding cassette sub-family G member 2	transporter
DB12001	Abemaciclib	Solute carrier family 22 member 2	transporter
DB12001	Abemaciclib	Cytochrome P450 1A2	enzyme
DB12001	Abemaciclib	Cytochrome P450 2B6	enzyme
DB12001	Abemaciclib	Cytochrome P450 2C8	enzyme
DB12001	Abemaciclib	Cytochrome P450 2C9	enzyme
DB12001	Abemaciclib	Cytochrome P450 2D6	enzyme
DB09074	Olaparib	Poly [ADP-ribose] polymerase 1	target
DB09074	Olaparib	Cytochrome P450 3A4	enzyme
DB09074	Olaparib	Cytochrome P450 2B6	enzyme
DB09074	Olaparib	Poly [ADP-ribose] polymerase 2	target
DB09074	Olaparib	Poly [ADP-ribose] polymerase 3	target
DB09074	Olaparib	Cytochrome P450 3A5	enzyme
DB09074	Olaparib	P-glycoprotein 1	transporter
DB09074	Olaparib	ATP-binding cassette sub-family G member 2	transporter
DB09074	Olaparib	Aldo-keto reductase family 1 member C3	target
DB09074	Olaparib	UDP-glucuronosyltransferase 1-1	enzyme
DB09074	Olaparib	Serum albumin	carrier
DB09074	Olaparib	Alpha-1-acid glycoprotein 1	carrier

Drug	Drug Name	Phase	Status	Count
DB01217	Anastrozole	Not Available	Unknown Status	1
DB00990	Exemestane	Not Available	Unknown Status	1
DB00675	Tamoxifen	Not Available	Unknown Status	1