Subtilisin DY

Details

Name
Subtilisin DY
Synonyms
  • 3.4.21.62
Gene Name
apr
Organism
Bacillus licheniformis
Amino acid sequence
>lcl|BSEQ0012612|Subtilisin DY
AQTVPYGIPLIKADKVQAQGYKGANVKVGIIDTGIAASHTDLKVVGGASFVSGESYNTDG
NGHGTHVAGTVAALDNTTGVLGVAPNVSLYAIKVLNSSGSGTYSAIVSGIEWATQNGLDV
INMSLGGPSGSTALKQAVDKAYASGIVVVAAAGNSGSSGSQNTIGYPAKYDSVIAVGAVD
SNKNRASFSSVGAELEVMAPGVSVYSTYPSNTYTSLNGTSMASPHVAGAAALILSKYPTL
SASQVRNRLSSTATNLGDSFYYGKGLINVEAAAQ
Number of residues
274
Molecular Weight
27435.335
Theoretical pI
7.77
GO Classification
Functions
metal ion binding / serine-type endopeptidase activity
Processes
sporulation resulting in formation of a cellular spore
Components
extracellular region
General Function
Serine-type endopeptidase activity
Specific Function
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Secreted
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP00781
UniProtKB Entry NameSUBD_BACLI
General References
  1. Nedkov P, Oberthur W, Braunitzer G: [Primary structure of subtilisin DY]. Hoppe Seylers Z Physiol Chem. 1983 Nov;364(11):1537-40. [Article]
  2. Eschenburg S, Genov N, Peters K, Fittkau S, Stoeva S, Wilson KS, Betzel C: Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg. Eur J Biochem. 1998 Oct 15;257(2):309-18. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB06886N-BENZYLOXYCARBONYL-ALA-PRO-3-AMINO-4-PHENYL-BUTAN-2-OLexperimentalunknownDetails