Interferon alpha-2
Details
- Name
- Interferon alpha-2
- Synonyms
- IFN-alpha-2
- IFNA2A
- IFNA2B
- IFNA2C
- Interferon alpha-A
- LeIF A
- Gene Name
- IFNA2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0019425|Interferon alpha-2 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFG FPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEA CVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNL QESLRSKE
- Number of residues
- 188
- Molecular Weight
- 21549.765
- Theoretical pI
- 6.75
- GO Classification
- Functionscytokine activity / type I interferon receptor bindingProcessesadaptive immune response / apoptotic process / B cell differentiation / B cell proliferation / blood coagulation / cell surface receptor signaling pathway / cell-cell signaling / cytokine-mediated signaling pathway / defense response to virus / humoral immune response / inflammatory response / innate immune response / natural killer cell activation involved in immune response / negative regulation of gene expression / negative regulation of interleukin-13 secretion / negative regulation of interleukin-5 secretion / negative regulation of T cell differentiation / negative regulation of T-helper 2 cell cytokine production / negative regulation of transcription, DNA-templated / negative regulation of viral entry into host cell / positive regulation of peptidyl-serine phosphorylation of STAT protein / positive regulation of phosphorylation / positive regulation of transcription, DNA-templated / positive regulation of tyrosine phosphorylation of Stat3 protein / regulation of type I interferon-mediated signaling pathway / response to exogenous dsRNA / T cell activation involved in immune response / type I interferon signaling pathwayComponentsextracellular region / extracellular space
- General Function
- Type i interferon receptor binding
- Specific Function
- Produced by macrophages, IFN-alpha have antiviral activities.
- Pfam Domain Function
- Interferon (PF00143)
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0019426|Interferon alpha-2 (IFNA2) ATGGCCTTGACCTTTGCTTTACTGGTGGCCCTCCTGGTGCTCAGCTGCAAGTCAAGCTGC TCTGTGGGCTGTGATCTGCCTCAAACCCACAGCCTGGGTAGCAGGAGGACCTTGATGCTC CTGGCACAGATGAGGAGAATCTCTCTTTTCTCCTGCTTGAAGGACAGACATGACTTTGGA TTTCCCCAGGAGGAGTTTGGCAACCAGTTCCAAAAGGCTGAAACCATCCCTGTCCTCCAT GAGATGATCCAGCAGATCTTCAATCTCTTCAGCACAAAGGACTCATCTGCTGCTTGGGAT GAGACCCTCCTAGACAAATTCTACACTGAACTCTACCAGCAGCTGAATGACCTGGAAGCC TGTGTGATACAGGGGGTGGGGGTGACAGAGACTCCCCTGATGAAGGAGGACTCCATTCTG GCTGTGAGGAAATACTTCCAAAGAATCACTCTCTATCTGAAAGAGAAGAAATACAGCCCT TGTGCCTGGGAGGTTGTCAGAGCAGAAATCATGAGATCTTTTTCTTTGTCAACAAACTTG CAAGAAAGTTTAAGAAGTAAGGAATGA
- Chromosome Location
- 9
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P01563 UniProtKB Entry Name IFNA2_HUMAN GenBank Gene ID M29883 GenAtlas ID IFNA2 HGNC ID HGNC:5423 - General References
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