Ig alpha-2 chain C region
Details
- Name
- Ig alpha-2 chain C region
- Synonyms
- Not Available
- Gene Name
- IGHA2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009530|Ig alpha-2 chain C region ASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDAS GDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVPPPPPCCHPRLSLHRPA LEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCA QPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLAR GFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSC MVGHEALPLAFTQKTIDRMAGKPTHVNVSVVMAEVDGTCY
- Number of residues
- 340
- Molecular Weight
- 36526.005
- Theoretical pI
- Not Available
- GO Classification
- Functionsantigen bindingProcessesantibacterial humoral response / B cell receptor signaling pathway / complement activation, classical pathway / Fc-epsilon receptor signaling pathway / Fc-gamma receptor signaling pathway involved in phagocytosis / glomerular filtration / immune response / innate immune response / phagocytosis, engulfment / phagocytosis, recognition / positive regulation of B cell activation / positive regulation of respiratory burst / receptor-mediated endocytosis / retina homeostasisComponentsblood microparticle / external side of plasma membrane / extracellular exosome / extracellular region / extracellular space / monomeric IgA immunoglobulin complex / secretory dimeric IgA immunoglobulin complex / secretory IgA immunoglobulin complex
- General Function
- Antigen binding
- Specific Function
- Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
- Pfam Domain Function
- C1-set (PF07654)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P01877 UniProtKB Entry Name IGHA2_HUMAN HGNC ID HGNC:5479 - General References
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