4-alpha-glucanotransferase
Details
- Name
- 4-alpha-glucanotransferase
- Synonyms
- 2.4.1.25
- Amylomaltase
- D-enzyme
- Disproportionating enzyme
- Gene Name
- mgtA
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Amino acid sequence
>lcl|BSEQ0011186|4-alpha-glucanotransferase MIGYQIYVRSFRDGNLDGVGDFRGLKNAVSYLKELGIDFVWLMPVFSSISFHGYDVVDFY SFKAEYGSEREFKEMIEAFHDSGIKVVLDLPIHHTGFLHTWFQKALKGDPHYRDYYVWAN KETDLDERREWDGEKIWHPLEDGRFYRGLFGPFSPDLNYDNPQVFDEMKRLVLHLLDMGV DGFRFDAAKHMRDTIEQNVRFWKYFLSDLKGIFLAEIWAEARMVDEHGRIFGYMLNFDTS HCIKEAVWKENTRVLIESIERAVIGKDYLPVNFTSNHDMSRLASFEGGFSKEKIKLSISI LFTLPGVPLVFYGDELGMKGVYQKPNTEVVLDPFPWNESMCVEGQTFWKWPAYNGPFSGI SVEYQKRDPDSILSHTLGWTRFRKENQWIDRAKLEFLCKEDKFLVYRLYDDQHSLKVFHN LSGEEVVFEGVKMKPYKTEVV
- Number of residues
- 441
- Molecular Weight
- 51842.69
- Theoretical pI
- 5.74
- GO Classification
- Functions4-alpha-glucanotransferase activity / metal ion bindingComponentscytoplasm
- General Function
- Metal ion binding
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011187|4-alpha-glucanotransferase (mgtA) ATGATAGGCTATCAGATCTACGTGAGATCTTTCAGGGATGGAAACCTCGACGGTGTGGGA GATTTCAGGGGATTGAAAAACGCTGTTTCCTACCTGAAAGAACTGGGGATTGACTTTGTC TGGCTCATGCCTGTTTTTTCCTCCATATCTTTTCACGGGTACGACGTGGTGGATTTTTAT TCTTTCAAAGCTGAGTACGGTAGTGAGAGAGAGTTCAAAGAGATGATCGAGGCATTCCAC GACAGCGGAATAAAAGTCGTTCTTGACCTTCCCATCCATCACACAGGCTTTCTCCACACG TGGTTCCAGAAGGCGCTGAAAGGAGATCCACACTACAGAGATTACTACGTATGGGCAAAC AAAGAGACGGATCTGGACGAAAGAAGAGAGTGGGATGGAGAAAAGATCTGGCATCCCCTG GAAGATGGGAGGTTCTACAGAGGGCTCTTTGGACCTTTCTCACCCGACTTGAACTACGAC AACCCGCAGGTATTCGATGAAATGAAAAGACTGGTTCTCCACCTTCTCGATATGGGAGTG GATGGTTTCAGGTTCGATGCAGCAAAGCACATGAGAGATACGATCGAACAGAATGTTCGC TTCTGGAAGTACTTTCTTTCCGATTTGAAGGGCATCTTCCTCGCAGAGATATGGGCAGAG GCCAGAATGGTGGATGAACACGGCAGAATATTTGGCTACATGCTCAACTTTGACACATCC CACTGTATAAAGGAAGCTGTATGGAAAGAGAACACAAGAGTTCTGATAGAGTCGATCGAA AGGGCCGTTATCGGCAAAGACTACCTCCCGGTGAATTTTACTTCGAATCACGACATGTCG AGGCTTGCAAGCTTTGAAGGAGGCTTCAGCAAAGAAAAGATCAAACTTTCGATTTCCATT CTTTTCACTCTCCCGGGAGTTCCTCTCGTGTTCTATGGGGATGAGCTTGGAATGAAGGGA GTTTACCAGAAACCGAACACAGAAGTCGTCCTGGATCCGTTCCCGTGGAACGAGAGTATG TGCGTTGAGGGACAGACCTTCTGGAAGTGGCCCGCGTACAACGGGCCTTTCTCTGGTATC TCCGTAGAATACCAGAAGAGAGATCCCGATTCGATTCTTTCACACACTCTGGGATGGACG AGATTCAGAAAGGAAAACCAGTGGATCGATCGGGCAAAGCTCGAATTTTTGTGTAAAGAG GACAAGTTTCTTGTGTACAGACTCTACGATGATCAGCATTCTTTGAAGGTGTTTCACAAT CTTTCAGGGGAAGAGGTTGTCTTTGAGGGAGTTAAAATGAAGCCTTACAAAACGGAGGTG GTTTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P80099 UniProtKB Entry Name MGTA_THEMA GenBank Protein ID 4980866 GenBank Gene ID AE000512 - General References
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
- Liebl W, Feil R, Gabelsberger J, Kellermann J, Schleifer KH: Purification and characterization of a novel thermostable 4-alpha-glucanotransferase of Thermotoga maritima cloned in Escherichia coli. Eur J Biochem. 1992 Jul 1;207(1):81-8. [Article]
- Roujeinikova A, Raasch C, Sedelnikova S, Liebl W, Rice DW: Crystal structure of Thermotoga maritima 4-alpha-glucanotransferase and its acarbose complex: implications for substrate specificity and catalysis. J Mol Biol. 2002 Aug 2;321(1):149-62. [Article]