Tumor necrosis factor receptor superfamily member 9
Details
- Name
- Tumor necrosis factor receptor superfamily member 9
- Synonyms
- 4-1BB ligand receptor
- CD137
- CDw137
- ILA
- T-cell antigen 4-1BB homolog
- T-cell antigen ILA
- Gene Name
- TNFRSF9
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0012418|Tumor necrosis factor receptor superfamily member 9 MGNSCYNIVATLLLVLNFERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQR TCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDC CFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPARE PGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPVQTTQEEDG CSCRFPEEEEGGCEL
- Number of residues
- 255
- Molecular Weight
- 27898.6
- Theoretical pI
- 7.77
- GO Classification
- Functionsreceptor activity / tumor necrosis factor-activated receptor activityProcessesapoptotic process / extrinsic apoptotic signaling pathway via death domain receptors / immune response / inflammatory response / multicellular organismal development / negative regulation of cell proliferation / negative regulation of interleukin-10 secretion / negative regulation of interleukin-12 secretion / protein homotrimerization / regulation of apoptotic process / response to lipopolysaccharide / tumor necrosis factor-mediated signaling pathwayComponentsexternal side of plasma membrane / extracellular space / integral component of plasma membrane
- General Function
- Tumor necrosis factor-activated receptor activity
- Specific Function
- Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
- Pfam Domain Function
- TNFR_c6 (PF00020)
- Transmembrane Regions
- 187-213
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0012419|Tumor necrosis factor receptor superfamily member 9 (TNFRSF9) ATGGGAAACAGCTGTTACAACATAGTAGCCACTCTGTTGCTGGTCCTCAACTTTGAGAGG ACAAGATCATTGCAGGATCCTTGTAGTAACTGCCCAGCTGGTACATTCTGTGATAATAAC AGGAATCAGATTTGCAGTCCCTGTCCTCCAAATAGTTTCTCCAGCGCAGGTGGACAAAGG ACCTGTGACATATGCAGGCAGTGTAAAGGTGTTTTCAGGACCAGGAAGGAGTGTTCCTCC ACCAGCAATGCAGAGTGTGACTGCACTCCAGGGTTTCACTGCCTGGGGGCAGGATGCAGC ATGTGTGAACAGGATTGTAAACAAGGTCAAGAACTGACAAAAAAAGGTTGTAAAGACTGT TGCTTTGGGACATTTAACGATCAGAAACGTGGCATCTGTCGACCCTGGACAAACTGTTCT TTGGATGGAAAGTCTGTGCTTGTGAATGGGACGAAGGAGAGGGACGTGGTCTGTGGACCA TCTCCAGCCGACCTCTCTCCGGGAGCATCCTCTGTGACCCCGCCTGCCCCTGCGAGAGAG CCAGGACACTCTCCGCAGATCATCTCCTTCTTTCTTGCGCTGACGTCGACTGCGTTGCTC TTCCTGCTGTTCTTCCTCACGCTCCGTTTCTCTGTTGTTAAACGGGGCAGAAAGAAACTC CTGTATATATTCAAACAACCATTTATGAGACCAGTACAAACTACTCAAGAGGAAGATGGC TGTAGCTGCCGATTTCCAGAAGAAGAAGAAGGAGGATGTGAACTGTGA
- Chromosome Location
- 1
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q07011 UniProtKB Entry Name TNR9_HUMAN GenBank Gene ID BC006196 GenAtlas ID TNFRSF9 HGNC ID HGNC:11924 - General References
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