Enolase

Details

Name

Enolase

Synonyms

• 2-phospho-D-glycerate hydro-lyase
• 2-phosphoglycerate dehydratase
• 4.2.1.11

Gene Name

ENO

Organism

Fasciola hepatica

Amino acid sequence

>lcl|BSEQ0052095|Enolase
MAIKAIHARQIFDSRGNPTVEVDVTTAKGLFRAAVPSGASTGVHEALELRDGPPGYMGKG
VLKAVANVNSQIAPNLIKSGINVTDQAAVDKFMLDLDGTPNKEKLGANAILGVSLAXCKA
GAAEKGLPLYKYIATLAGNKEVIMPVPSFNVINGGSHAGNKLAMQEFMIMPTGASSFTEA
MKIGSEVYHNLRAVIKSKYGLDACNVGDEGGFAPSIQDNLEGLELLRTAIDKAGYTGKVX
IAMDCAASEFYKEGKYDLDFKNPKSQASSWITSDAMADVYKKMMSTYPIVSIEDPFDQDD
WPAWTKLTGECKIQIVGDDLTVTNPLRVQKAIDQKACNCLLLKVNQIGSVSESIKACKMA
QEAGWGVMVSHRSGETEDNFIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEDLGGA
AKYAGENFRRP

Number of residues

431

Molecular Weight

Not Available

Theoretical pI

Not Available

GO Classification

Functions

magnesium ion binding / phosphopyruvate hydratase activity

Processes

glycolytic process

Components

phosphopyruvate hydratase complex

General Function

Not Available

Specific Function

Magnesium ion binding

Pfam Domain Function

• Enolase_C (PF00113)
• Enolase_N (PF03952)

Transmembrane Regions

Not Available

Cellular Location

Cytoplasm

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q27655
UniProtKB Entry Name	ENO_FASHE

General References

1. Davis RE, Singh H, Botka C, Hardwick C, Ashraf el Meanawy M, Villanueva J: RNA trans-splicing in Fasciola hepatica. Identification of a spliced leader (SL) RNA and SL sequences on mRNAs. J Biol Chem. 1994 Aug 5;269(31):20026-30. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB12245	Triclabendazole	approved, investigational	unknown	inhibitor	Details