Mitogen-activated protein kinase kinase kinase 19
Details
- Name
- Mitogen-activated protein kinase kinase kinase 19
- Synonyms
- 2.7.11.1
- RCK
- Regulated in COPD, protein kinase
- SPS1/STE20-related protein kinase YSK4
- YSK4
- Gene Name
- MAP3K19
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0051694|Mitogen-activated protein kinase kinase kinase 19 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP HFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS LTSFVPKLSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQ CLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPE EENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRNNKAASKRV SLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSR MVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDS KTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKK QSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGP GIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKK THMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSK DEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQEL EELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHS KTLTNFSFQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSV NNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTK VKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLT SQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGII KLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEM ATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK HSFLERSH
- Number of residues
- 1328
- Molecular Weight
- 150536.265
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / protein serine/threonine kinase activityProcessesactivation of protein kinase activity / regulation of apoptotic process / regulation of mitotic cell cycle / signal transduction by protein phosphorylation / stress-activated protein kinase signaling cascadeComponentscytoplasm
- General Function
- Not Available
- Specific Function
- Atp binding
- Pfam Domain Function
- Pkinase (PF00069)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0051695|Mitogen-activated protein kinase kinase kinase 19 (MAP3K19) ATGAGTTCTATGCCAAAACCAGAAAGACATGCTGAGTCATTGCTTGACATTTGTCATGAT ACAAACTCTTCTCCAACTGATTTGATGACAGTTACCAAAAATCAAAACATCATCTTGCAA AGCATCAGCAGAAGTGAGGAGTTCGACCAAGATGGTGACTGCAGTCATTCCACACTGGTT AATGAAGAAGAAGATCCCAGTGGTGGTAGACAGGACTGGCAACCCAGGACAGAAGGTGTT GAGATCACTGTAACTTTTCCAAGAGATGTCAGTCCTCCCCAAGAAATGAGCCAAGAAGAC TTAAAAGAAAAGAATCTGATAAACTCATCGCTTCAAGAATGGGCACAAGCACATGCAGTT TCTCATCCAAATGAAATAGAAACGGTGGAGCTCAGGAAAAAGAAGCTGACCATGCGGCCC TTAGTTTTGCAAAAAGAGGAAAGTTCCAGGGAGCTCTGCAATGTGAACTTGGGCTTTTTG CTACCAAGATCTTGTTTAGAACTGAACATTTCCAAGTCTGTAACCAGAGAAGATGCTCCT CATTTTCTGAAGGAGCAGCAAAGAAAATCTGAAGAGTTTTCGACCTCTCATATGAAGTAC AGTGGCCGAAGCATCAAGTTCCTTCTGCCACCACTGTCACTCTTGCCCACGCGATCTGGT GTCCTTACTATCCCCCAAAATCACAAGTTTCCAAAAGAAAAAGAAAGAAACATTCCAAGT CTCACATCTTTTGTGCCTAAGCTCTCAGTGTCTGTTCGTCAATCTGATGAGCTCAGCCCA TCAAACGAGCCTCCGGGAGCCCTAGTTAAGTCGTTGATGGATCCGACTCTCAGGTCTTCT GATGGCTTCATTTGGTCAAGAAACATGTGCTCTTTTCCTAAGACTAACCATCACAGGCAA TGCCTGGAGAAGGAGGAAAACTGGAAATCCAAGGAAATAGAAGAATGTAACAAAATTGAA ATCACTCACTTTGAAAAAGGGCAGTCTTTGGTGTCTTTTGAGAATTTGAAGGAAGGCAAT ATTCCTGCAGTTAGGGAAGAGGATATTGACTGCCATGGTAGTAAAACGCGAAAACCTGAA GAAGAGAACTCTCAATATCTTTCATCAAGAAAGAATGAGAGTTCAGTAGCCAAAAACTAT GAACAAGATCCAGAAATAGTATGTACCATTCCAAGCAAGTTCCAAGAAACCCAGCATTCA GAAATAACTCCAAGCCAGGATGAAGAGATGAGAAATAATAAAGCTGCTTCAAAAAGAGTT TCATTACATAAAAATGAAGCAATGGAACCAAACAATATTTTAGAAGAGTGTACTGTACTT AAAAGCTTATCCAGTGTAGTCTTTGATGACCCCATTGATAAACTCCCAGAAGGTTGTAGC AGCATGGAGACAAACATAAAAATATCAATAGCAGAAAGAGCCAAACCAGAAATGAGTAGG ATGGTGCCTCTTATCCACATCACCTTCCCTGTGGATGGAAGCCCCAAGGAACCAGTGATA GCCAAACCAAGCCTCCAAACAAGAAAGGGAACCATTCATAACAACCATAGTGTCAACATA CCTGTACACCAAGAAAATGACAAGCATAAGATGAATTCCCATAGGAGTAAGTTGGATTCA AAGACCAAGACAAGTAAGAAGACACCTCAGAATTTTGTGATTTCTACTGAAGGTCCCATT AAGCCTACCATGCATAAAACCAGCATAAAAACACAAATTTTCCCGGCTTTGGGACTTGTG GACCCCAGGCCTTGGCAATTGCCCAGGTTTCAAAAGAAAATGCCACAGATAGCAAAGAAG CAATCAACTCACCGGACTCAGAAACCTAAAAAGCAATCATTTCCTTGCATCTGTAAAAAT CCAGGAACACAGAAGTCATGTGTTCCTCTCTCTGTTCAACCGACAGAGCCAAGACTAAAT TACCTAGATCTTAAGTATAGTGATATGTTCAAAGAAATCAATTCAACTGCTAATGGACCT GGAATCTATGAAATGTTTGGGACCCCTGTTTATTGTCATGTGCGAGAGACTGAAAGGGAT GAAAACACGTATTACCGTGAGATATGTTCGGCTCCATCAGGCAGACGTATCACCAATAAA TGTCGATCTTCACACAGTGAGAGGAAGAGCAATATCAGAACAAGACTTTCTCAGAAAAAA ACACATATGAAATGCCCAAAGACTTCATTTGGCATTAAACAAGAGCACAAAGTCTTAATT TCTAAAGAAAAGAGTTCCAAGGCTGTACATAGCAACCTACATGACATTGAAAATGGTGAT GGTATTTCAGAACCAGACTGGCAGATAAAGTCTTCAGGAAATGAGTTTCTATCTTCCAAA GATGAAATTCATCCCATGAACTTGGCTCAGACACCTGAGCAGTCCATGAAACAGAATGAA TTCCCTCCTGTCTCAGATTTATCCATTGTTGAAGAAGTTTCTATGGAAGAGTCTACTGGT GATAGAGACATTTCTAACAATCAAATACTCACCACAAGCCTCAGAGATCTGCAAGAACTT GAAGAGCTACATCACCAGATCCCATTTATCCCTTCAGAAGACAGCTGGGCAGTGCCCAGT GAGAAGAATTCTAACAAGTATGTACAGCAAGAAAAGCAGAATACAGCATCTCTTAGTAAA GTAAATGCCAGCCGAATTTTAACTAATGATCTAGAGTTTGATAGTGTTTCAGATCACTCT AAAACACTTACAAATTTCTCTTTCCAAGCAAAACAAGAAAGTGCATCTTCCCAGACATAT CAATATTGGGTACATTATTTGGATCATGATAGTTTAGCAAATAAGTCAATCACATATCAA ATGTTTGGAAAAACCTTAAGTGGCACAAATTCAATTTCCCAAGAAATTATGGACTCTGTA AATAATGAAGAATTGACAGATGAACTATTAGGTTGTCTAGCTGCAGAATTATTAGCTCTT GATGAGAAAGATAACAACTCTTGCCAAAAAATGGCAAATGAAACAGATCCTGAAAACCTA AATCTTGTCCTCAGATGGAGAGGAAGTACCCCAAAAGAAATGGGCAGAGAGACAACAAAA GTCAAAATACAGAGGCATAGTAGTGGGCTCAGGATATATGACAGGGAGGAGAAATTTCTC ATCTCAAATGAAAAGAAGATATTTTCTGAAAATAGTTTAAAGTCTGAAGAACCTATCCTA TGGACCAAGGGTGAGATTCTTGGAAAGGGAGCCTACGGCACAGTATACTGTGGTCTCACT AGTCAAGGACAGCTAATAGCTGTAAAACAGGTGGCTTTGGATACCTCTAATAAATTAGCT GCTGAAAAGGAATACCGGAAACTACAGGAAGAAGTAGATTTGCTCAAAGCACTGAAACAT GTCAACATTGTGGCCTATTTGGGGACATGCTTGCAAGAGAACACTGTGAGCATTTTCATG GAGTTTGTTCCTGGTGGCTCAATCTCTAGTATTATAAACCGTTTTGGGCCATTGCCTGAG ATGGTGTTCTGTAAATATACGAAACAAATACTTCAAGGTGTTGCTTATCTCCATGAGAAC TGTGTGGTACATCGCGATATCAAAGGAAATAATGTTATGCTCATGCCAACTGGAATAATA AAGCTGATTGACTTTGGCTGTGCCAGGCGTTTGGCCTGGGCAGGTTTAAATGGCACCCAC AGTGACATGCTTAAGTCCATGCATGGGACTCCATATTGGATGGCCCCAGAAGTCATCAAT GAGTCTGGCTATGGACGGAAATCAGATATCTGGAGCATTGGTTGTACTGTGTTTGAGATG GCTACAGGGAAGCCTCCACTGGCTTCCATGGACAGGATGGCCGCCATGTTTTACATCGGA GCACACCGAGGGCTGATGCCTCCTTTACCAGACCACTTCTCAGAAAATGCAGCAGACTTT GTGCGCATGTGCCTGACCAGGGACCAGCATGAGCGACCTTCTGCTCTCCAGCTCCTGAAG CACTCCTTCTTGGAGAGAAGTCACTGA
- Chromosome Location
- 2
- Locus
- 2q21.3
- External Identifiers
Resource Link UniProtKB ID Q56UN5 UniProtKB Entry Name M3K19_HUMAN HGNC ID HGNC:26249 - General References
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