Bifunctional purine biosynthesis protein PurH
Details
- Name
- Bifunctional purine biosynthesis protein PurH
- Synonyms
- 2.1.2.3
- Gene Name
- purH
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Amino acid sequence
>lcl|BSEQ0011972|Bifunctional purine biosynthesis protein PurH MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGG LVKTLHPEIFAGILGPEPRWDVVFVDLYPPPDIDIGGVALLRAAAKNWKKVKPAFDMETL KLAIEIDDEETRKYLAGMTFAFTSVYDSIRANQFVEGISLAFKREDLQLRYGENPHEKAF VYGKPAFEILHEGKTISFNNILDAENAWFMAKNLPRMGAVVVKHQSPCGAAIGEDKVEIV KKAIEADDESSFGGILAVNFEMDEEVAKSLKKYLEVIVAPSFTQEAIEVLSKKKVRLLKP GDYASWAGKMAFGSLVLSERKYPEGNFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLI AKDGVTVGIGSGQPSRKRAAWIATVMAGEKAKGAVAASDAFFPFPDSLEILAQAGVKAVV APLGSIRDEEVIEKARELGITFYKAPSRVFRH
- Number of residues
- 452
- Molecular Weight
- 49866.915
- Theoretical pI
- 5.32
- GO Classification
- FunctionsIMP cyclohydrolase activity / phosphoribosylaminoimidazolecarboxamide formyltransferase activityProcesses'de novo' IMP biosynthetic process
- General Function
- Phosphoribosylaminoimidazolecarboxamide formyltransferase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0011973|Bifunctional purine biosynthesis protein PurH (purH) TTGAAGAGGATATTGGTTAGTCTCTACGAGAAAGAAAAATATCTGGATATTCTGAGAGAA CTCCACGAAAAAGGCTGGGAGATCTGGGCGAGCTCCGGCACCGCCAAGTTTTTGAAATCA AACGGAATAGAAGCAAACGACGTGAGCACCATAACGGGTTTCGAGAATCTCCTCGGAGGG CTCGTGAAGACCCTCCACCCGGAGATATTCGCCGGCATCCTCGGACCGGAACCCAGATGG GATGTGGTCTTTGTGGACCTATATCCACCCCCAGACATCGACATAGGAGGAGTCGCTCTT CTTCGAGCAGCTGCCAAAAACTGGAAAAAGGTGAAACCCGCTTTCGACATGGAAACACTC AAACTCGCGATTGAGATAGACGACGAAGAGACGAGAAAGTACCTCGCTGGAATGACCTTT GCGTTCACCAGTGTGTACGATTCGATAAGGGCCAACCAGTTTGTCGAGGGTATTTCTCTC GCCTTCAAGAGGGAAGATCTTCAGCTGAGGTACGGAGAGAACCCTCACGAAAAAGCGTTT GTGTATGGAAAACCAGCTTTTGAGATTCTGCACGAAGGAAAGACAATCTCATTCAACAAC ATCTTAGACGCGGAAAACGCGTGGTTCATGGCGAAGAACCTGCCGAGGATGGGTGCGGTT GTGGTGAAACACCAATCTCCCTGTGGTGCTGCGATAGGAGAAGACAAAGTGGAAATCGTG AAGAAGGCCATCGAGGCGGACGACGAATCCAGTTTTGGAGGGATCCTGGCCGTGAACTTC GAAATGGACGAAGAAGTTGCGAAGTCATTGAAAAAGTACCTCGAGGTGATCGTGGCACCT TCCTTCACACAGGAAGCGATCGAGGTTCTCTCTAAGAAAAAAGTGCGTCTCTTGAAGCCT GGGGATTACGCTTCGTGGGCTGGAAAGATGGCATTCGGTTCTCTCGTCCTGAGTGAAAGA AAGTACCCCGAAGGGAATTTTGAACTGGTAGTTGGAGAGCCTCTCTCGGAAAAAGAGCTT GAGGATCTGGAATTCGCTTACCGTGTTGTGGAAGGAGCGAAATCCAACGCTGTTCTCATA GCAAAAGACGGTGTAACTGTGGGAATAGGGAGCGGGCAGCCTTCGAGAAAGAGAGCTGCC TGGATCGCCACCGTGATGGCAGGAGAAAAAGCGAAGGGAGCGGTTGCGGCTTCCGATGCG TTCTTCCCGTTCCCGGACTCGCTCGAAATACTCGCTCAGGCTGGTGTGAAAGCGGTGGTC GCTCCTCTCGGATCCATAAGAGACGAAGAAGTGATCGAAAAAGCCAGAGAACTTGGAATC ACGTTCTACAAAGCTCCGAGCAGGGTTTTCAGGCACTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9X0X6 UniProtKB Entry Name PUR9_THEMA GenBank Gene ID AE000512 - General References
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details