Reaction: Nicardipine to 1 product

Reaction
Reaction type
Heteroring dehydrogenation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Brown CM, Reisfeld B, Mayeno AN: Cytochromes P450: a structure-based summary of biotransformations using representative substrates. Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742 . [PubMed:18259985]
  2. Rendic S: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448. [PubMed:11996015]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A1Not AvailableNot Availableimplied
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2C8Not AvailableNot Availableimplied
Cytochrome P450 2D6Not AvailableNot Availableimplied
Cytochrome P450 2E1Not AvailableNot Availableimplied
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 3A5Not AvailableNot Availableimplied