Reaction: Imatinib to 1 product

Reaction
Reaction type
benzyl hydroxylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Rochat B, Zoete V, Grosdidier A, von Grunigen S, Marull M, Michielin O: In vitro biotransformation of imatinib by the tumor expressed CYP1A1 and CYP1B1. Biopharm Drug Dispos. 2008 Mar;29(2):103-18. doi: 10.1002/bdd.598. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableconfirmed
Cytochrome P450 1A1Not AvailableNot Availableimplied
Cytochrome P450 1B1Not AvailableNot Availableimplied
Cytochrome P450 4F3Not AvailableNot Availableimplied