Reaction: S-4'-hydroxybupropion to 1 product
- Reaction
- Reaction type
- ketoreduction
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Not Available
- Comments
- Aflatoxin B1 aldehyde reductase member 3 (AKR7) is the main enzyme that catalyzes the reaction in the intestine, while corticosteroid 11-beta dehydrogenase (HSD11B1) is the main enzyme responsible in the liver.[A247010]
- Enzymes
Enzyme Km Vmax Role Corticosteroid 11-beta-dehydrogenase isozyme 1 Not Available Not Available implied Aflatoxin B1 aldehyde reductase member 3 Not Available Not Available implied