Reaction: Bupropion to 1 product
- Reaction
- Reaction type
- Aliphatic hydroxylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Chen Y, Liu HF, Liu L, Nguyen K, Jones EB, Fretland AJ: The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19. Xenobiotica. 2010 Aug;40(8):536-46. doi: 10.3109/00498254.2010.492880. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 2C19 Not Available Not Available confirmed