Reaction: Hydroxyurea to 3 products

Reaction
Hydroxyurea
DB01005
    Ammonia
    DBMET01482
    Carbon dioxide
    DBMET00137
    Hydroxylamine
    DBMET03681
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Yahouedehou SCMA, Adorno EV, da Guarda CC, Ndidi US, Carvalho SP, Santiago RP, Aleluia MM, de Oliveira RM, Goncalves MS: Hydroxyurea in the management of sickle cell disease: pharmacogenomics and enzymatic metabolism. Pharmacogenomics J. 2018 Dec;18(6):730-739. doi: 10.1038/s41397-018-0045-1. Epub 2018 Sep 12. [Article]
    Comments
    Not Available
    Enzymes
    Not Available