Reaction: Pitavastatin to 1 product

Reaction
Pitavastatin
DB08860
Pitavastatin glucuronide
DBMET03739
Reaction type
O-glucuronidation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
unknown
References
  1. Saito Y: Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals. Vasc Health Risk Manag. 2009;5:921-36. doi: 10.2147/vhrm.s5551. Epub 2009 Nov 16. [Article]
  2. FDA Approved Drug Products: NIKITATM (pitavastatin) tablets, for oral use (November 2023) [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-3Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 1-1Not AvailableNot Availableimplied