Besifloxacin hydrochlorideProduct ingredient for Besifloxacin
- Name
- Besifloxacin hydrochloride
- Drug Entry
- Besifloxacin
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
- Accession Number
- DBSALT000018
- Structure
- Synonyms
- Not Available
- External IDs
- BOL-303224-A / SS734
- UNII
- 7506A6J57T
- CAS Number
- 405165-61-9
- Weight
- Average: 430.301
Monoisotopic: 429.102225204 - Chemical Formula
- C19H22Cl2FN3O3
- InChI Key
- PMQBICKXAAKXAY-HNCPQSOCSA-N
- InChI
- InChI=1S/C19H21ClFN3O3.ClH/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23;/h7,9-11H,1-6,8,22H2,(H,26,27);1H/t10-;/m1./s1
- IUPAC Name
- 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- SMILES
- Cl.[H][C@@]1(N)CCCCN(C1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1Cl)C(O)=O
- External Links
- PubChem Compound
- 10224595
- ChemSpider
- 8400086
- ChEBI
- 775712
- ChEMBL
- CHEMBL1201761
- Wikipedia
- Besifloxacin
- Predicted Properties
Property Value Source Water Solubility 0.143 mg/mL ALOGPS logP 0.7 ALOGPS logP 0.54 Chemaxon logS -3.4 ALOGPS pKa (Strongest Acidic) 5.45 Chemaxon pKa (Strongest Basic) 9.84 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 86.87 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 101.75 m3·mol-1 Chemaxon Polarizability 38.93 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon