Cysteamine bitartrateProduct ingredient for Cysteamine

Name
Cysteamine bitartrate
Drug Entry
Cysteamine

Cysteamine is a radiation-protective agent that oxidizes in air to form cystamine. It can be given intravenously or orally to treat radiation sickness. The bitartrate and hydrochloride salt forms are indicated for the treatment of neuropathic cystinosis in patients 6 years old and older. Cysteamine is marketed under several brand names such as Cystaran, Procysbi, and Cystagon.

Accession Number
DBSALT000032
Structure
Thumb
Synonyms
Not Available
UNII
QO84GZ3TST
CAS Number
27761-19-9
Weight
Average: 227.236
Monoisotopic: 227.046357843
Chemical Formula
C6H13NO6S
InChI Key
NSKJTUFFDRENDM-UHFFFAOYSA-N
InChI
InChI=1S/C4H6O6.C2H7NS/c5-1(3(7)8)2(6)4(9)10;3-1-2-4/h1-2,5-6H,(H,7,8)(H,9,10);4H,1-3H2
IUPAC Name
2,3-dihydroxybutanedioic acid; 2-aminoethane-1-thiol
SMILES
NCCS.OC(C(O)C(O)=O)C(O)=O
External Links
PubChem Compound
23111531
ChemSpider
16135851
ChEBI
50386
ChEMBL
CHEMBL2062263
Wikipedia
Cysteamine
Predicted Properties
PropertyValueSource
Water Solubility161.0 mg/mLALOGPS
logP-1.3ALOGPS
logP-1.8ChemAxon
logS0.03ALOGPS
pKa (Strongest Acidic)2.72ChemAxon
pKa (Strongest Basic)-4.3ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area115.06 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity26.21 m3·mol-1ChemAxon
Polarizability11.61 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon