Buformin hydrochlorideProduct ingredient for Buformin
- Name
- Buformin hydrochloride
- Drug Entry
- Buformin
Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.
- Accession Number
- DBSALT000336
- Structure
Structure for Buformin hydrochloride (DBSALT000336)
- Synonyms
- Buformin HCl
- UNII
- D947SXO87P
- CAS Number
- 1190-53-0
- Weight
- Average: 193.678
Monoisotopic: 193.109423244 - Chemical Formula
- C6H16ClN5
- InChI Key
- KKLWSPPIRBIEOV-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H15N5.ClH/c1-2-3-4-10-6(9)11-5(7)8;/h2-4H2,1H3,(H6,7,8,9,10,11);1H
- IUPAC Name
- N-butyl-1-carbamimidamidomethanimidamide hydrochloride
- SMILES
- Cl.CCCCNC(=N)NC(N)=N
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.76 mg/mL ALOGPS logP -1.2 ALOGPS logP 0.14 Chemaxon logS -2.3 ALOGPS pKa (Strongest Basic) 12.13 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 97.78 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 65.22 m3·mol-1 Chemaxon Polarizability 17.61 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon