Edrophonium chlorideProduct ingredient for Edrophonium

Name
Edrophonium chloride
Drug Entry
Edrophonium

A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.

Accession Number
DBSALT000475
Structure
Thumb
Synonyms
Not Available
UNII
QO611KSM5P
CAS Number
116-38-1
Weight
Average: 201.693
Monoisotopic: 201.092041846
Chemical Formula
C10H16ClNO
InChI Key
BXKDSDJJOVIHMX-UHFFFAOYSA-N
InChI
InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
IUPAC Name
3-(ethyldimethylazaniumyl)benzen-1-olate hydrochloride
SMILES
Cl.CC[N+](C)(C)C1=CC([O-])=CC=C1
External Links
PubChem Compound
8307
ChemSpider
8006
ChEBI
4759
ChEMBL
CHEMBL1128
Wikipedia
Edrophonium
Predicted Properties
PropertyValueSource
Water Solubility0.0113 mg/mLALOGPS
logP-1.8ALOGPS
logP-1.9ChemAxon
logS-4.3ALOGPS
pKa (Strongest Acidic)8.59ChemAxon
pKa (Strongest Basic)-6.1ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area23.06 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity72.96 m3·mol-1ChemAxon
Polarizability18.8 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon