Cefmenoxime hydrochlorideProduct ingredient for Cefmenoxime
- Name
- Cefmenoxime hydrochloride
- Drug Entry
- Cefmenoxime
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
- Accession Number
- DBSALT000801
- Structure
- Synonyms
- Cefmenoxime HCl
- UNII
- NON736D32W
- CAS Number
- 75738-58-8
- Weight
- Average: 548.019
Monoisotopic: 547.028154508 - Chemical Formula
- C16H18ClN9O5S3
- InChI Key
- HZYJYGJIOCXOTH-FAIYLGIWSA-N
- InChI
- InChI=1S/C16H17N9O5S3.ClH/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b21-8-;/t9-,13-;/m1./s1
- IUPAC Name
- (6R,7R)-7-{[(2Z)-1-hydroxy-2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)ethylidene]amino}-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
- SMILES
- Cl.[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@@]2([H])N=C(O)C(=N/OC)\C1=CSC(=N)N1)C(O)=O
- External Links
- PubChem Compound
- 9690105
- ChemSpider
- 7962939
- ChEBI
- 775037
- Wikipedia
- Cefmenoxime
- Predicted Properties
Property Value Source Water Solubility 1.56 mg/mL ALOGPS logP 0.39 ALOGPS logP -1.2 Chemaxon logS -2.5 ALOGPS pKa (Strongest Acidic) 2.58 Chemaxon pKa (Strongest Basic) 9.84 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 12 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 191.27 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 146.82 m3·mol-1 Chemaxon Polarizability 48.46 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon