Phencyclidine hydrochlorideProduct ingredient for Phencyclidine

Name
Phencyclidine hydrochloride
Drug Entry
Phencyclidine

A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust.

Accession Number
DBSALT000824
Structure
Thumb
Synonyms
Phencyclidine HCl
UNII
V1JZQ7GDTX
CAS Number
956-90-1
Weight
Average: 279.848
Monoisotopic: 279.175377544
Chemical Formula
C17H26ClN
InChI Key
BUAJNGPDPGKBGV-UHFFFAOYSA-N
InChI
InChI=1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H
IUPAC Name
1-(1-phenylcyclohexyl)piperidine hydrochloride
SMILES
Cl.C1CCN(CC1)C1(CCCCC1)C1=CC=CC=C1
External Links
PubChem Compound
13727
ChemSpider
13132
ChEBI
644096
ChEMBL
CHEMBL542581
Predicted Properties
PropertyValueSource
Water Solubility0.00325 mg/mLALOGPS
logP5.31ALOGPS
logP4.49ChemAxon
logS-4.9ALOGPS
pKa (Strongest Basic)10.64ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area3.24 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity77.65 m3·mol-1ChemAxon
Polarizability29.82 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon