Phencyclidine hydrochlorideProduct ingredient for Phencyclidine
- Name
- Phencyclidine hydrochloride
- Drug Entry
- Phencyclidine
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust.
- Accession Number
- DBSALT000824
- Structure
Structure for Phencyclidine hydrochloride (DBSALT000824)
- Synonyms
- Phencyclidine HCl
- UNII
- V1JZQ7GDTX
- CAS Number
- 956-90-1
- Weight
- Average: 279.848
Monoisotopic: 279.175377544 - Chemical Formula
- C17H26ClN
- InChI Key
- BUAJNGPDPGKBGV-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H
- IUPAC Name
- 1-(1-phenylcyclohexyl)piperidine hydrochloride
- SMILES
- Cl.C1CCN(CC1)C1(CCCCC1)C1=CC=CC=C1
- External Links
- PubChem Compound
- 13727
- ChemSpider
- 13132
- ChEBI
- 644096
- ChEMBL
- CHEMBL542581
- Predicted Properties
Property Value Source Water Solubility 0.00325 mg/mL ALOGPS logP 5.31 ALOGPS logP 4.49 Chemaxon logS -4.9 ALOGPS pKa (Strongest Basic) 10.56 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 3.24 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 77.65 m3·mol-1 Chemaxon Polarizability 29.82 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon