Isopropamide iodideProduct ingredient for Isopropamide
- Name
- Isopropamide iodide
- Drug Entry
- Isopropamide
Isopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
- Accession Number
- DBSALT001023
- Structure
- Synonyms
- Not Available
- UNII
- E0KNA372SZ
- CAS Number
- 71-81-8
- Weight
- Average: 480.434
Monoisotopic: 480.16376 - Chemical Formula
- C23H33IN2O
- InChI Key
- BFSMWENDZZIWPW-UHFFFAOYSA-N
- InChI
- InChI=1S/C23H32N2O.HI/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21;/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26);1H
- IUPAC Name
- (3-carbamoyl-3,3-diphenylpropyl)(methyl)bis(propan-2-yl)azanium iodide
- SMILES
- [I-].CC(C)[N+](C)(CCC(C(N)=O)(C1=CC=CC=C1)C1=CC=CC=C1)C(C)C
- External Links
- ChemSpider
- 6047
- ChEBI
- 6044
- ChEMBL
- CHEMBL1200347
- Wikipedia
- Isopropamide
- Predicted Properties
Property Value Source Water Solubility 6.7e-05 mg/mL ALOGPS logP -0.17 ALOGPS logP 0.14 Chemaxon logS -6.9 ALOGPS pKa (Strongest Acidic) 16.31 Chemaxon pKa (Strongest Basic) -3.3 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 43.09 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 120.74 m3·mol-1 Chemaxon Polarizability 41.23 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon