Tetracaine hydrochlorideProduct ingredient for Tetracaine

Name
Tetracaine hydrochloride
Drug Entry
Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Accession Number
DBSALT001125
Structure
Thumb
Synonyms
Tetracaine HCl
UNII
5NF5D4OPCI
CAS Number
136-47-0
Weight
Average: 300.83
Monoisotopic: 300.1604558
Chemical Formula
C15H25ClN2O2
InChI Key
PPWHTZKZQNXVAE-UHFFFAOYSA-N
InChI
InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
IUPAC Name
2-(dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride
SMILES
Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
External Links
ChemSpider
8371
ChEBI
9469
ChEMBL
CHEMBL1255654
Wikipedia
Tetracaine
Predicted Properties
PropertyValueSource
Water Solubility0.555 mg/mLALOGPS
logP3.54ALOGPS
logP2.79ChemAxon
logS-2.7ALOGPS
pKa (Strongest Basic)8.42ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area41.57 Å2ChemAxon
Rotatable Bond Count9ChemAxon
Refractivity80.17 m3·mol-1ChemAxon
Polarizability31.9 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon