Proguanil hydrochlorideProduct ingredient for Proguanil

Name
Proguanil hydrochloride
Drug Entry
Proguanil

Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.

Accession Number
DBSALT001187
Structure
Thumb
Synonyms
Proguanil HCl
UNII
R71Y86M0WT
CAS Number
637-32-1
Weight
Average: 290.19
Monoisotopic: 289.086101
Chemical Formula
C11H17Cl2N5
InChI Key
SARMGXPVOFNNNG-UHFFFAOYSA-N
InChI
InChI=1S/C11H16ClN5.ClH/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9;/h3-7H,1-2H3,(H5,13,14,15,16,17);1H
IUPAC Name
SMILES
Cl.CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1
External Links
ChemSpider
4514300
ChEMBL
CHEMBL1201059
Wikipedia
Proguanil
Predicted Properties
PropertyValueSource