Naratriptan hydrochlorideProduct ingredient for Naratriptan
- Name
- Naratriptan hydrochloride
- Drug Entry
- Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
- Accession Number
- DBSALT001246
- Structure
- Synonyms
- Naratriptan HCl
- UNII
- 10X8X4P12Z
- CAS Number
- 143388-64-1
- Weight
- Average: 371.92
Monoisotopic: 371.143426 - Chemical Formula
- C17H26ClN3O2S
- InChI Key
- AWEZYKMQFAUBTD-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
- IUPAC Name
- N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide hydrochloride
- SMILES
- Cl.CNS(=O)(=O)CCC1=CC2=C(NC=C2C2CCN(C)CC2)C=C1
- External Links
- ChemSpider
- 54857
- ChEBI
- 7479
- ChEMBL
- CHEMBL1200601
- Wikipedia
- Naratriptan
- Predicted Properties
Property Value Source Water Solubility 0.114 mg/mL ALOGPS logP 2.16 ALOGPS logP 1.44 Chemaxon logS -3.5 ALOGPS pKa (Strongest Acidic) 11.55 Chemaxon pKa (Strongest Basic) 9.18 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 65.2 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 94.26 m3·mol-1 Chemaxon Polarizability 37.65 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon