Sulbactam sodiumProduct ingredient for Sulbactam

Name
Sulbactam sodium
Drug Entry
Sulbactam

Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity.

Accession Number
DBSALT001310
Structure
Thumb
Synonyms
Not Available
External IDs
CP 458992 / CP-45899-2 / CP-458992 / CP458992
UNII
DKQ4T82YE6
CAS Number
69388-84-7
Weight
Average: 255.22
Monoisotopic: 255.01773788
Chemical Formula
C8H10NNaO5S
InChI Key
NKZMPZCWBSWAOX-IBTYICNHSA-M
InChI
InChI=1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
IUPAC Name
sodium (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
SMILES
[Na+].CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
External Links
KEGG Compound
C14001
ChemSpider
571120
ChEMBL
CHEMBL1200944
Wikipedia
Sulbactam
Predicted Properties
PropertyValueSource
Water Solubility33.8 mg/mLALOGPS
logP-0.1ALOGPS
logP-0.89ChemAxon
logS-0.88ALOGPS
pKa (Strongest Acidic)3.09ChemAxon
pKa (Strongest Basic)-3.8ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area94.58 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity59.05 m3·mol-1ChemAxon
Polarizability20.19 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon