Penciclovir sodiumProduct ingredient for Penciclovir

Name
Penciclovir sodium
Drug (Active Moiety)
Penciclovir

Penciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. [Wikipedia]

Accession Number
DBSALT001449
Structure
Thumb
Synonyms
Not Available
UNII
P06226385L
CAS Number
97845-62-0
Weight
Average: 275.244
Monoisotopic: 275.09943361
Chemical Formula
C10H14N5NaO3
InChI Key
NMQFQBOIHUIALG-UHFFFAOYSA-M
InChI
InChI=1S/C10H15N5O3.Na/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17;/h5-6,16-17H,1-4H2,(H3,11,13,14,18);/q;+1/p-1
IUPAC Name
sodium 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6-oxo-6,9-dihydro-1H-purin-1-ide
SMILES
[Na+].NC1=NC2=C(N=CN2CCC(CO)CO)C(=O)[N-]1
External Links
ChemSpider
28524083
ChEMBL
CHEMBL2079793
Wikipedia
Penciclovir
Predicted Properties
PropertyValueSource
Water Solubility12.1 mg/mLALOGPS
logP-1.4ALOGPS
logP-2.1ChemAxon
logS-1.4ALOGPS
pKa (Strongest Acidic)10.17ChemAxon
pKa (Strongest Basic)0.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count7ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area122.96 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity64.23 m3·mol-1ChemAxon
Polarizability24.88 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon