Metralindole hydrochlorideProduct ingredient for Metralindole

Show full entry for Metralindole
Name
Metralindole hydrochloride
Drug Entry
Metralindole

Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. In Russia, this drug was investigated for potential antidepressant activity.

See full entry for Metralindole
Accession Number
DBSALT001789
Structure
Similar Structures
Synonyms
Metralindole HCl
UNII
M15TM76Y3L
CAS Number
53734-79-5
Weight
Average: 291.78
Monoisotopic: 291.1138399
Chemical Formula
C15H18ClN3O
InChI Key
RQQVSZWEVNAKGW-UHFFFAOYSA-N
InChI
InChI=1S/C15H17N3O.ClH/c1-17-7-8-18-13-4-3-10(19-2)9-12(13)11-5-6-16-15(17)14(11)18;/h3-4,9H,5-8H2,1-2H3;1H
IUPAC Name
12-methoxy-4-methyl-1,4,6-triazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-5,9(16),10(15),11,13-pentaene hydrochloride
SMILES
Cl.COC1=CC2=C(C=C1)N1CCN(C)C3=NCCC2=C13
ChemSpider
149758
ChEMBL
CHEMBL1388946
Predicted Properties
PropertyValueSource
Water Solubility0.367 mg/mLALOGPS
logP1.62ALOGPS
logP1.61Chemaxon
logS-2.8ALOGPS
pKa (Strongest Basic)8.95Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area29.76 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity75.95 m3·mol-1Chemaxon
Polarizability28.97 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon