MesnaProduct ingredient for Coenzyme M
- Name
- Mesna
- Drug Entry
- Coenzyme M
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.2
- Accession Number
- DBSALT002380
- Structure
Structure for Mesna (DBSALT002380)
- Synonyms
- Coenzyme M sodium salt / Mesnex / Sodium 2-mercaptoethane sulfonate / Sodium 2-mercaptoethanesulfonate / Sodium 2-mercaptoethanesulphonate / Sodium 2-sulphanylethanesulphonate
- External IDs
- D 7093 / D-7093 / NSC-113891
- UNII
- NR7O1405Q9
- CAS Number
- 19767-45-4
- Weight
- Average: 164.17
Monoisotopic: 163.95778065 - Chemical Formula
- C2H5NaO3S2
- InChI Key
- XOGTZOOQQBDUSI-UHFFFAOYSA-M
- InChI
- InChI=1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
- IUPAC Name
- sodium 2-sulfanylethane-1-sulfonate
- SMILES
- [Na+].[O-]S(=O)(=O)CCS
- External Links
- Predicted Properties
Property Value Source Water Solubility 13.3 mg/mL ALOGPS logP -0.01 ALOGPS logP -0.4 Chemaxon logS -1.1 ALOGPS pKa (Strongest Acidic) -1.2 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 57.2 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 28.01 m3·mol-1 Chemaxon Polarizability 12.12 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon