Choline tetrathiomolybdateProduct ingredient for Tetrathiomolybdate
- Name
- Choline tetrathiomolybdate
- Drug Entry
- Tetrathiomolybdate
Tetrathiomolybdate is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease. It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body.
- Accession Number
- DBSALT003343
- Structure
Structure for Choline tetrathiomolybdate (DBSALT003343)
- Synonyms
- bis-choline tetrathiomolybdate / Bis(choline) tetrathiomolybdate / ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, (T-4)-TETRATHIOXOMOLYBDATE(2-) (2:1) / Tiomolibdate choline
- External IDs
- ALXN-1840
- UNII
- FD57A79R4P
- CAS Number
- 649749-10-0
- Weight
- Average: 432.54
Monoisotopic: 434.008768 - Chemical Formula
- C10H28MoN2O2S4
- InChI Key
- NEYVHGQOGHJAAD-UHFFFAOYSA-N
- InChI
- InChI=1S/2C5H14NO.Mo.4S/c2*1-6(2,3)4-5-7;;;;;/h2*7H,4-5H2,1-3H3;;;;;/q2*+1;;;;2*-1
- IUPAC Name
- bis((2-hydroxyethyl)trimethylazanium); (sulfanidyldisulfanylidenemolybdenio)sulfanide
- SMILES
- [S-][Mo]([S-])(=S)=S.C[N+](C)(C)CCO.C[N+](C)(C)CCO
- External Links
- ChemSpider
- 19906891
- Wikipedia
- Tiomolibdic_acid
- Predicted Properties
Property Value Source logP -4.7 Chemaxon pKa (Strongest Acidic) 13.97 Chemaxon pKa (Strongest Basic) -3.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 42.19 m3·mol-1 Chemaxon Polarizability 12.57 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon