Alendronate disodiumProduct ingredient for Alendronic acid
- Name
- Alendronate disodium
- Drug Entry
- Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's diseaseLabel1,5. It functions by preventing resorption of boneLabel1.
- Accession Number
- DBSALT003348
- Structure
Structure for Alendronate disodium (DBSALT003348)
- Synonyms
- Not Available
- UNII
- I2U0WCC042
- CAS Number
- 134606-40-9
- Weight
- Average: 293.059
Monoisotopic: 292.98061425 - Chemical Formula
- C4H11NNa2O7P2
- InChI Key
- LMWOPQOPFYJQLI-UHFFFAOYSA-L
- InChI
- InChI=1S/C4H13NO7P2.2Na/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;/q;2*+1/p-2
- IUPAC Name
- disodium hydrogen (4-amino-1-hydrogen phosphonato-1-hydroxybutyl)phosphonate
- SMILES
- [Na+].[Na+].NCCCC(O)(P(O)([O-])=O)P(O)([O-])=O
- External Links
- ChemSpider
- 16463512
- Predicted Properties
Property Value Source logP -4.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 166.97 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 45.13 m3·mol-1 Chemaxon Polarizability 18.48 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon