Vamifeport hydrochlorideProduct ingredient for Vamifeport
- Name
- Vamifeport hydrochloride
- Drug Entry
- Vamifeport
Vamifeport is being investigated for the treatment of beta-thalassemia.
- Accession Number
- DBSALT003352
- Structure
Structure for Vamifeport hydrochloride (DBSALT003352)
- Synonyms
- 2-(2-((2-(1H-benzimidazol-2-yl)ethyl]amino}ethyl)-N-((3-fluoropyridin-2-yl)methyl)-1,3-oxazole-4-carboxamide trihydrochloride / 2-(2-{[2-(1H-benzimidazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride
- UNII
- 9DV8VO33JX
- CAS Number
- 2095668-11-2
- Weight
- Average: 517.81
Monoisotopic: 516.1010353 - Chemical Formula
- C21H24Cl3FN6O2
- InChI Key
- ZBVCLZMNYXJVMV-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H21FN6O2.3ClH/c22-14-4-3-9-24-17(14)12-25-21(29)18-13-30-20(28-18)8-11-23-10-7-19-26-15-5-1-2-6-16(15)27-19;;;/h1-6,9,13,23H,7-8,10-12H2,(H,25,29)(H,26,27);3*1H
- IUPAC Name
- 2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride
- SMILES
- Cl.Cl.Cl.FC1=C(CNC(=O)C2=COC(CCNCCC3=NC4=CC=CC=C4N3)=N2)N=CC=C1
- External Links
- ChemSpider
- 128718076
- ChEMBL
- CHEMBL4475199
- Predicted Properties
Property Value Source logP 1.3 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 108.73 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 107.34 m3·mol-1 Chemaxon Polarizability 43.19 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon