CB-103 hydrochlorideProduct ingredient for CB-103
- Name
- CB-103 hydrochloride
- Drug Entry
- CB-103
CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).
- Accession Number
- DBSALT003418
- Structure
Structure for CB-103 hydrochloride (DBSALT003418)
- Synonyms
- 6-(4-(tert-butyl)phenoxy)pyridin-3-amine hydrochloride
- UNII
- 37VB9K7MPR
- CAS Number
- Not Available
- Weight
- Average: 278.78
Monoisotopic: 278.1185909 - Chemical Formula
- C15H19ClN2O
- InChI Key
- WLUQNBKZPMQGJG-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H18N2O.ClH/c1-15(2,3)11-4-7-13(8-5-11)18-14-9-6-12(16)10-17-14;/h4-10H,16H2,1-3H3;1H
- IUPAC Name
- 6-(4-tert-butylphenoxy)pyridin-3-amine hydrochloride
- SMILES
- Cl.CC(C)(C)C1=CC=C(OC2=CC=C(N)C=N2)C=C1
- External Links
- Not Available
- Predicted Properties
Property Value Source logP 3.57 Chemaxon pKa (Strongest Basic) 2.38 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 48.14 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 73.82 m3·mol-1 Chemaxon Polarizability 27.26 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon