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Displaying all 2 drugs
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … all-cause mortality, including fatal and non-fatal CVD, as well as the need for surgical revascularization or ... revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or …
Ezetimibe
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Description: … does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or …
Displaying all 2 drugs