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Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Synonyms: … Cedazuridine
Matched Name: … Cedazuridine
Matched Description: … [A215082, A215092, A215097] Hypomethylating agents such as [decitabine] and [azacitidine] are used to ... [A215107, A215112, A215117, A215127, L14897] Cedazuridine was first reported in 2014,[A215107] and ... was subsequently approved by the FDA on July 7, 2020, in combination with [decitabine] for sale by Astex …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … Decitabine
Matched Name: … Decitabine
Matched Description: … [A215082, A215092] Among treatment options, nucleoside analogues such as decitabine and [azacitidine] ... [A2263, A2264, A2265, A215317, L14962] Decitabine was developed by MGI Pharma/SuperGen Inc. and was ... It is also available as an oral combination product together with the cytidine deaminase inhibitor [cedazuridine
Matched Categories: … decitabine ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Decitabine ... Redtibin (Decitabine) Powder for Injection 50mg/vial ... DACOGEN (Decitabine) 50 mg Powder for Concentrate for Solution for Infusion …
Displaying all 2 drugs