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A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Hyaluronidase human recombinant ... Hyaluronidase (human recombinant) ... Hyaluronidase recombinant human
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese ... A purified preparation of the enzyme recombinant human hyaluronidase. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … Hyaluronidase ... HYLENEX Recombinant ... HYLENEX Recombinant Professional Sample …
Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction. The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in...
Approved
Investigational
Matched Synonyms: … Efgartigimod alfa
Matched Name: … Efgartigimod alfa
Matched Description: … [L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was approved ... Efgartigimod alfa for intravenous use was granted FDA approval on December 17, 2021[L39501] and European ... [L39509] By antagonizing this interaction, efgartigimod alfa prevents this recycling phase and thus decreases …
Matched Categories: … efgartigimod alfa ... Human Immunoglobulin G ... Antineoplastic and Immunomodulating Agents …
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR ... Pegvorhyaluronidase alfa
Matched Name: … Pegvorhyaluronidase alfa
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single ... Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). …
Matched Categories: … Enzymes and Coenzymes …
Displaying all 3 drugs