Displaying drugs 3551 - 3575 of 11853 in total
Pyrophosphoric acid
Approved
Experimental
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Tripelennamine
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Approved
Vet approved
Matched Description: … A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. …
Diethylcarbamazine
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Approved
Investigational
Vet approved
Lebrikizumab
Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared tralokinumab.[A262874,A262879]
On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight...
Approved
Investigational
Matched Description: … Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared [tralokinumab ... treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a …
Propiverine
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) .
Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency, increased frequency of urination, and nocturia (frequent waking during the...
Approved
Investigational
Matched Description: … Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms ... OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents ... Overactive bladder (OAB) is a chronic condition of the lower urinary tract characterized by urinary urgency …
Indapamide
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204134,A204161]
Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide ... [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... [A204155]
Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension …
Sodium sulfate
Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions. Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Sodium sulfate...
Approved
Vet approved
Matched Description: … Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of …
Raltitrexed
Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Approved
Investigational
Matched Description: … Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence ... fluorescent signal that can be detected using a fluorescence imaging device. ... The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. ... Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting ... Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses …
Tyrosine
Tyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.
Approved
Investigational
Nutraceutical
Matched Description: … Tyrosine is a non-essential amino acid. In animals it is synthesized from [phenylalanine]. …
Cetirizine
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Tafenoquine
Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group.[A35671, A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria. Tafenoquine was...
Approved
Investigational
Matched Description: … Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy ... A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a …
Isosorbide
Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational
Prochlorperazine
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Description: … Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic …
Evinacumab
Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind. The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in...
Approved
Investigational
Matched Description: … rationale for the development of a therapy targeted against ANGPTL3. ... Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein ... The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the …
Regdanvimab
Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding ... Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Aspergillus nidulans
Aspergillus nidulans is a fungus which can provoke allergic reactions. Aspergillus nidulans extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus nidulans is a fungus which can provoke allergic reactions. …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … a higher diuretic potential. ... Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in …
Acacia dealbata pollen
Acacia dealbata pollen allergenic extract is used in allergenic testing.
Approved
Displaying drugs 3551 - 3575 of 11853 in total