Displaying drugs 4176 - 4200 of 11735 in total
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
RGX-111
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
B7-H3-specific chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3 ... chimeric antigen receptor (CAR) modified recombinant T cells targeting B7-H3 ... allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR) …
OriCar-017
Investigational
Matched Synonyms: … GPRC5D-CAR-T ... chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D …
Dordaviprone
Dordaviprone (ONC-201) is under investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma).
Investigational
Matched Synonyms: … 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin ... 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one …
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide is a solid. This compound belongs to the penicillins. These are organic compounds containing the penicillin core structure, which is structurally characterized by a penam ring bearing two methyl groups at position 2, and an amide group at position 6 [starting from the sulfur atom at position 1]. This...
Experimental
Matched Name: … N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept …
Matched Description: … -6-yl]-2-phenylacetamide is a solid. ... N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept ... organic compounds containing the penicillin core structure, which is structurally characterized by a …
Matched Description: … -6-yl]-2-phenylacetamide is a solid. ... N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept ... organic compounds containing the penicillin core structure, which is structurally characterized by a …
(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE
Experimental
Matched Name: … ,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A] …
Matched Iupac: … 9bS,11aR)-11a-{2-[(3,5-difluorophenyl)methoxy]ethyl}-1-hydroxy-9a-methyl-hexadecahydro-1H-cyclopenta[a] …
Matched Iupac: … 9bS,11aR)-11a-{2-[(3,5-difluorophenyl)methoxy]ethyl}-1-hydroxy-9a-methyl-hexadecahydro-1H-cyclopenta[a] …
4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE
Experimental
Matched Name: … 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN …
Matched Iupac: … 4-[(3aS,4R,7R,8aS,8bR)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-7-hydroxy-1,3-dioxo-decahydropyrrolo[3,4-a] …
Matched Iupac: … 4-[(3aS,4R,7R,8aS,8bR)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-7-hydroxy-1,3-dioxo-decahydropyrrolo[3,4-a] …
Mimopezil
Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease. Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A.
Investigational
Matched Synonyms: … N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A …
Matched Description: … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. …
Matched Description: … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. …
Esmirtazapine
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Matched Synonyms: … (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine …
Eluvixtamab
Investigational
Matched Synonyms: … A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy …
20-Hydroxyecdysone
Investigational
Matched Synonyms: … Polypodin a ... Polypodine a …
Matched Iupac: … 2,3,6-trihydroxy-6-methylheptan-2-yl]-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Iupac: … 2,3,6-trihydroxy-6-methylheptan-2-yl]-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Exaluren
Investigational
Matched Synonyms: … 6-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine ... 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine …
DCP-001
Investigational
Matched Synonyms: … Proliferation arrested myelomonocytic leukemic cell line-derived cells with a mature dendritic cell phenotype …
alpha-Pinene
Experimental
Matched Synonyms: … Acintene A …
Matched Iupac: … 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene …
Matched Iupac: … 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene …
Cyclo(prolylglycyl)
Experimental
Matched Synonyms: … (S)-Hexahydropyrrolo(1,2-a)pyrazine-1,4-dione-4-17O …
Matched Iupac: … (8aS)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Iupac: … (8aS)-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
CTX130
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
4-Amino-1-[(1s,3r,4r,7s)-7-Hydroxy-1-(Hydroxymethyl)-2,5-Dioxabicyclo[2.2.1]Hept-3-Yl]-5-Methylpyrimidin-2(1h)-One
Experimental
Matched Name: … 4-Amino-1-[(1s,3r,4r,7s)-7-Hydroxy-1-(Hydroxymethyl)-2,5-Dioxabicyclo[2.2.1]Hept-3-Yl]-5-Methylpyrimidin …
Aclerastide
Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Investigational
Matched Synonyms: … NorLeu3-A(1-7) ... NorLeu3-Angiotensin(1-7) [NorLeu3-A(1-7)] …
STRO-001
Investigational
Matched Synonyms: … STRO-001, a site-specific anti-CD74 antibody-drug conjugate ... antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
Adinazolam
Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was first developed to enhance the antidepressant effects of alprazolam. It has never been approved by the FDA for clinical use.
Experimental
Matched Synonyms: … 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant …
Matched Description: … Adinazolam (Deracyn®) is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant …
Go-6976
An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Investigational
Matched Synonyms: … 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo- …
Displaying drugs 4176 - 4200 of 11735 in total